M. Orho-Melander

Latest

• The PNPLA3-I148M variant increases polyunsaturated triglycerides in human adipose tissue
• Human PNPLA3-I148M variant increases hepatic retention of polyunsaturated fatty acids
• Saturated Fat Is More Metabolically Harmful for the Human Liver Than Unsaturated Fat or Simple Sugars
• Predictors of Liver Fat and Stiffness in Non-Alcoholic Fatty Liver Disease (NAFLD) - an 11-Year Prospective Study
• Impaired hepatic lipid synthesis from polyunsaturated fatty acids in TM6SF2 E167K variant carriers with NAFLD
• Obesity/insulin resistance rather than liver fat increases coagulation factor activities and expression in humans
• The MBOAT7 variant rs641738 alters hepatic phosphatidylinositols and increases severity of non-alcoholic fatty liver disease in humans
• Circulating triacylglycerol signatures and insulin sensitivity in NAFLD associated with the E167K variant in TM6SF2
• A population-based study on the prevalence of NASH using scores validated against liver histology