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Actin Cytoskeleton/genetics/metabolism; Biological Transport/genetics; Cell Cycle Proteins/genetics; Cell Line; Cell Movement/genetics; Cell Proliferation/genetics; Chaperonins/genetics; Energy Metabolism/genetics; Gene Knockout Techniques; HSP90 Heat-Shock Proteins; Humans; Lipid Metabolism/genetics; Organelles/genetics/metabolism; Proto-Oncogene Proteins c-akt/genetics/metabolism; RNA
OSBP-related protein-2 (ORP2): a novel Akt effector that controls cellular energy metabolism
ORP2 is a ubiquitously expressed OSBP-related protein previously implicated in endoplasmic reticulum (ER)-lipid droplet (LD) contacts, triacylglycerol (TG) metabolism, cholesterol transport, adrenocortical steroidogenesis, and actin-dependent cell …