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adipose tissue; fatty acids; lipidomics; lipolysis; non-alcoholic fatty liver disease; triglycerides
The PNPLA3-I148M variant increases polyunsaturated triglycerides in human adipose tissue
BACKGROUND & AIMS: The I148M variant in PNPLA3 is the major genetic risk factor for non-alcoholic fatty liver disease (NAFLD). The liver is enriched with polyunsaturated triglycerides (PUFA-TGs) in PNPLA3-I148M carriers. Gene ression data indicate …