Western; Cell Line; Endosomes/metabolism/ultrastructure; Gene Silencing; Golgi Apparatus/metabolism/ultrastructure; Green Fluorescent Proteins/metabolism; Humans; Immunohistochemistry; Lipids/chemistry; Organ Specificity; Phosphatidylinositols/metabolism; Protein Binding; Protein Interaction Mapping; Protein Multimerization; Protein Structure

OSBP-related protein 11 (ORP11) dimerizes with ORP9 and localizes at the Golgi-late endosome interface

We characterize here ORP11, a member of the oxysterol-binding protein family. ORP11 is present at highest levels in human ovary, testis, kidney, liver, stomach, brain, and adipose tissue. Immunohistochemistry demonstrates abundant ORP11 in the …