V. M. Olkkonen

Latest

• A compound directed against S6K1 hampers fat mass expansion and mitigates diet-induced hepatosteatosis
• GOLM1 depletion modifies cellular sphingolipid metabolism and adversely affects cell growth
• Insulin-inducible THRSP maintains mitochondrial function and regulates sphingolipid metabolism in human adipocytes
• Protrudin regulates FAK activation, endothelial cell migration and angiogenesis
• ANGPTL3 deficiency alters the lipid profile and metabolism of cultured hepatocytes and human lipoproteins
• The PNPLA3-I148M variant increases polyunsaturated triglycerides in human adipose tissue
• Compounds that modulate AMPK activity and hepatic steatosis impact the biosynthesis of microRNAs required to maintain lipid homeostasis in hepatocytes
• OSBP-related protein-2 (ORP2): a novel Akt effector that controls cellular energy metabolism
• Analysis of ORP2-knockout hepatocytes uncovers a novel function in actin cytoskeletal regulation
• Angiopoietin-like 8 (Angptl8) controls adipocyte lipolysis and phospholipid composition
• Impaired hepatic lipid synthesis from polyunsaturated fatty acids in TM6SF2 E167K variant carriers with NAFLD
• Severe neurodegenerative disease in brothers with homozygous mutation in POLR1A
• Obesity/insulin resistance rather than liver fat increases coagulation factor activities and expression in humans
• MicroRNA-192* impairs adipocyte triglyceride storage
• Novel hepatic microRNAs upregulated in human nonalcoholic fatty liver disease
• OSBP-related protein 3 (ORP3) coupling with VAMP-associated protein A regulates R-Ras activity
• Impact of non-alcoholic fatty liver disease on liver volume in humans
• A vertebrate model for the study of lipid binding/transfer protein function: conservation of OSBP-related proteins between zebrafish and human
• OSBP-related protein 8 (ORP8) interacts with Homo sapiens sperm associated antigen 5 (SPAG5) and mediates oxysterol interference of HepG2 cell cycle
• PNPLA3 mediates hepatocyte triacylglycerol remodeling
• Association between baseline lipoprotein (a) levels and restenosis after coronary stenting: meta-analysis of 9 cohort studies
• Egg consumption and risk of bladder cancer: a meta-analysis
• Identification of urinary Gc-globulin as a novel biomarker for bladder cancer by two-dimensional fluorescent differential gel electrophoresis (2D-DIGE)
• OSBP-Related Proteins (ORPs) in Human Adipose Depots and Cultured Adipocytes: Evidence for Impacts on the Adipocyte Phenotype
• OSBP-related protein 7 interacts with GATE-16 and negatively regulates GS28 protein stability
• OSBP-related protein 11 (ORP11) dimerizes with ORP9 and localizes at the Golgi-late endosome interface