Actin Cytoskeleton/physiology; CRISPR-Cas Systems; Cell Adhesion; Cell Movement; Cell Proliferation; Gene Knockout Techniques; Hepatocytes/cytology/physiology; Humans; Receptors

ORP2 is implicated in cholesterol transport, triglyceride metabolism, and adrenocortical steroid hormone production. We addressed ORP2 function in hepatocytes by generating ORP2-knockout (KO) HuH7 cells by CRISPR-Cas9 gene editing, followed by …