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Angiopoietin like 3; Cholesterol ester; Lipid metabolism; Lipidomics; Lipoprotein lipase; Polyunsaturated fatty acid
ANGPTL3 deficiency alters the lipid profile and metabolism of cultured hepatocytes and human lipoproteins
Loss-of-function (LOF) mutations in ANGPTL3, an inhibitor of lipoprotein lipase (LPL), cause a drastic reduction of serum lipoproteins and pct against the development of atherosclerotic cardiovascular disease. Therefore, ANGPTL3 is a promising …